US findings suggesting ageing is not a slow and steady process could explain spikes in health issues at certain ages

If you have noticed a sudden accumulation of wrinkles, aches and pains or a general sensation of having grown older almost overnight, there may be a scientific explanation. Research suggests that rather than being a slow and steady process, aging occurs in at least two accelerated bursts.

The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages.

“We’re not just changing gradually over time. There are some really dramatic changes,” said Prof Michael Snyder, a geneticist and director of the Center for Genomics and Personalized Medicine at Stanford University and senior author of the study.

“It turns out the mid-40s is a time of dramatic change, as is the early 60s – and that’s true no matter what class of molecules you look at.”

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  • dmtalon@infosec.pub
    6·
    3 months ago

    Oh ya… Marathons have come and gone for me :) Initially because they were just expensive but COVID had me WFH full time and the group I ran with was near my work office. So I sort of morphed into running alone and just as maintenance vs. Training for something.

    I’m about to hit 53 and try to run between 15-20/miles a week still but I did fall behind on my fitness the end of last year when I had some crazy back spasms after sneezing (of all things) that really set me back. Takes forever to get back. Luckily I do not have any physical issues (knees etc) most if my issues now are not eating healthy enough and general motivation to improve. Sounds like I’ve got about 7 years to get on top of it so I can cruise through that age too :)

    • fpslem@lemmy.worldOP
      7·
      3 months ago

      back spasms after sneezing (of all things)

      This is the true humiliation of getting older. In my 20s I climbed mountains and had plenty of scrapes and mishaps, but I just shook them off and my body just healed up quickly. Now I can tweak my back with a sneeze or be sore for days just by raking leaves. Life comes at you fast.

      • dmtalon@infosec.pub
        4·
        3 months ago

        I literally could not get off the floor for around 2h and was panicking quite a bit. Never ever felt so vulnerable before. Do not recommend whatever happened to me :). Good thing is it was just muscle and once healed I was back to 100% It just prevented me from running for over a month.