In cases of cellular stress p53 is activated via phosphorylation. It will then direct the cell to pause its division and to either undergo DNA repair or kill itself. p53 is one of the body’s most important defences against cancer. Mutations causing p53 dysfunction are found in more than half of cancer cases.
May I ask what does it do?
In cases of cellular stress p53 is activated via phosphorylation. It will then direct the cell to pause its division and to either undergo DNA repair or kill itself. p53 is one of the body’s most important defences against cancer. Mutations causing p53 dysfunction are found in more than half of cancer cases.
Induces apoptosis in response to DNA damage (I think)