From a doctor in an online obesity clinic. They have a lot of clinical experience with semaglutide and tirzepitide. This is a link to their online practice. (Note that I am not a member or affiliated in any way.)

For the podcast, you can search “Beyond the Scale with Dr. Spencer Nodolsky” in your favorite app, and it’s available on YouTube as well.

I have listened to several episodes, and keep coming across interesting tidbits from their clinical practice. It isn’t entirely focused on GLP-1 medication, but you can pull out the ones with “GLP-1” in the title. It looks like they have been on a break since November, but they were using all of the current GLP-1s in their practice as of last Oct-Nov.

A few perspectives I have picked up from listening:

• It is important to eat enough on these meds. It’s healthier (from a psychological change-your-relationship-to-food perspective and from a physical health perspective) to get good nutrition and lose weight at a sustainable pace of <= 1.5% body weight per week. Use the med to help you eat smaller portions and avoid snacking, not to avoid eating all day.
• “Food Noise” reduction is a thing for most people they’ve seen. Although none of the meds were on-label for binge eating disorder, they have found that GLP-1’s are an excellent treatment for that, and they tied it to “food noise”.
• Most of the advice I’ve seen in this subreddit for side-effects is covered, and they offer some additional details, so worth a listen.
• They have seen both ends of the bell curve with hypo-and-hyper-responders to the meds. They usually try a different med to resolve that, but insurance can be a hassle in that case. Worth a listen if you are seeing good results with 2.5mg, or if you’re titrating up & results are still suboptimal.

I have only listened to a handful of episodes, but they have all had useful information. If you listen to podcasts (I like them while doing housework or working out), I recommend this one.