A case of rabies has been confirmed in a pet dog residing in the Capri area of the Southern Peninsula in Cape Town. The dog exhibited symptoms such as fever and increased aggression. Both the infected dog and a younger dog from the same household, which was injured, were humanely euthanized. The source of the infection is currently unclear, none of the dogs in the household had a recent travel history outside the province. Rabies is not endemic in wild animals in the City of Cape Town, with the closest wildlife cases in the past reported in the Paarl area. Recent investigations into reports of seals exhibiting aggressive behavior in the City found no evidence of rabies infection in seals.